Atomoxetine facilitates attentional set shifting in adolescent rats

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Atomoxetine facilitates attentional set shifting in adolescent rats

Adolescent rats show immaturities in executive function and are less able than adult rats to learn reinforcement reversals and shift attentional set. These two forms of executive function rely on the functional integrity of the orbitofrontal and prelimbic cortices respectively. Drugs used to treat attention deficit disorder, such as atomoxetine, that increase cortical catecholamine levels impro...

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ژورنال

عنوان ژورنال: Developmental Cognitive Neuroscience

سال: 2011

ISSN: 1878-9293

DOI: 10.1016/j.dcn.2011.04.003